Interchromosomal Huddle Kickstarts Antiviral Defense
نویسندگان
چکیده
Long-distance chromosomal interactions are emerging as a potential mechanism of gene expression control. In this issue, Apostolou and Thanos (2008) describe how viral infection elicits interchromosomal associations between the interferon-beta (IFN-beta) gene enhancer and DNA binding sites of the transcription factor NF-kappaB, resulting in the initiation of transcription and an antiviral response.
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عنوان ژورنال:
- Cell
دوره 134 شماره
صفحات -
تاریخ انتشار 2008